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| Game | Version | Protection | Version | Comments |
| Zanzarah | Phenoprotect | |||
| Zapper | SecuROM | 4.84.60.0002 | ||
| Zax: The Alien Hunter | SecuROM | 4.54.00.0001 | ||
| Zax: The Alien Hunter | 1.1 | SecuROM | 4.62.00.0003 | |
| Zeno Clash | 1.0 | Steam | ||
| Zeus: Master of Olympus | SecuROM | 4.32.00.0041 | ||
| Zombie Shooter 2 | 1.0 | StarForce | 5.70.7.2 | Russian |
| Zona | 1.0 | StarForce | 5.50.11.8 | Russian |
| Zoo Tycoon | SafeDisc | Lite | Safedisc Lite is similar to Safedisc 1 | |
| Zoo Tycoon 2 | SmartE | |||
| Zoo Tycoon 2 - Ultimate Collection | 1.0 | SafeDisc | 4.90.010 | |
