In fact I asked that because I was curious.

I have not found protection yet which resists to Daemon Tools.

But I just tried to use vUSB feature and after attaching a DT virtual drive to a free port it did nothing. I used usb controlers with and without device already listed but always free ports.

I even crashed windows explorer by unloading the usb driver after attaching a virtual drive to a controller which seems to be used by my external drive (event viewer said something about a driver reporting an error on the disk).

Is there a way to see if this is activated or not ?